Two sample MR report
TUFM_Monocyte (Mono) against UKB-b-18436
Date: 13 January, 2026
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 18 | 0.0077099 | 0.0515913 | 0.8830721 |
| Weighted median | 18 | 0.0393414 | 0.0080297 | 0.0000010 |
| Inverse variance weighted | 18 | 0.0373468 | 0.0061452 | 0.0000000 |
| Simple mode | 18 | 0.0463816 | 0.0133347 | 0.0028764 |
| Weighted mode | 18 | 0.0373314 | 0.0117851 | 0.0056252 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 13.31855 | 16 | 0.6493395 |
| Inverse variance weighted | 13.65330 | 17 | 0.6914737 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| 0.0140113 | 0.024217 | 0.5709322 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 0.0004067 | 0 | TRUE | 0.0565145 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
